Ubiquitination Factor E4A (UBE4A) (C-Term) Peptide
UBE4A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511620
Quick Overview for Ubiquitination Factor E4A (UBE4A) (C-Term) Peptide (ABIN5511620)
Target
UBE4A
(Ubiquitination Factor E4A (UBE4A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LAYARQASSQ ECIDVLLQYG CPDERFVLMA TPNLSRRNNN RNNSSGRVPT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- UBE4A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UBE4A (Ubiquitination Factor E4A (UBE4A))
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Background
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This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: E4, UFD2, UBOX2
Protein Size: 1066 -
Gene ID
- 9354
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NCBI Accession
- NM_001204077, NP_001191006
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UniProt
- Q14139
Target
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